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Article

Noncoding RNA-regulated gain-of-function of STOX2 in Finnish pre-eclamptic families.

Scientific reports - 24 Aug 2016

Oudejans Cees Bm, Poutsma Ankie, Michel Omar J, Thulluru Hari K, Mulders Joyce, van de Vrugt Henri J, Sistermans Erik A, van Dijk Marie

Abstract excerpt

The familial forms of early onset pre-eclampsia and related syndromes (HELLP) present with hypertension and proteinuria in the mother and growth restriction of the fetus. Genetically, these clinically similar entities are caused by different founder-dependent, placentally-expressed paralogous genes. All susceptibility genes (STOX1, lincHELLP, INO80B) identified so far are master control genes that regulate an...

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Source

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Identifiers

PMID: 27555360
DOI: 10.1038/srep32129
PMCID: PMC4995371

Genes

STOX2
CHD5
FGFR2
STOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Noncoding RNA-regulated gain-of-function of STOX2 in Finnish pre-eclamptic families.PMID 27555360Read ↗

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