Article
Functional Evaluation of STOX1 (STORKHEAD-BOX PROTEIN 1) in Placentation, Preeclampsia, and Preterm Birth.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2021
Dunk Caroline E, van Dijk Marie, Choudhury Ruhul, Wright Thomas J, Cox Brian, Leavey Katherine, Harris Lynda K, Jones Rebecca L, Lye Stephen J
Abstract excerpt
Revaluation of the association of the STOX1 (STORKHEAD_BOX1 PROTEIN 1) transcription factor mutation (Y153H, C allele) with the early utero-vascular origins of placental pathology is warranted. To investigate if placental STOX1 Y153H genotype affects utero-vascular remodeling-compromised in both preterm birth and preeclampsia-we utilized extravillous trophoblast (EVT) explant and placental decidual coculture...
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