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Article

Cytosolic phospholipase A2α increases proliferation and de-differentiation of human renal tubular epithelial cells.

Prostaglandins & other lipid mediators - 1 Nov 2016

Montford John R, Lehman Allison M B, Scobey Micah S, Weiser-Evans Mary C M, Nemenoff Raphael A, Furgeson Seth B

Abstract excerpt

The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme controls the release of arachidonic acid from membrane bound phospholipids and is the rate-limiting step in production of eicosanoids. A variety of different kidney injuries activate cPLA2α, therefore we hypothesized that cPLA2α activity would regulate pathologic processes in HK-2 cells, a human renal tubular epithelial cell line, by...

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Identifiers

PMID: 27554058
DOI: 10.1016/j.prostaglandins.2016.08.001
PMCID: PMC5099119

Genes

ZEB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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