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Article

Stratification and therapeutic potential of PML in metastatic breast cancer

24 Aug 2016

Abstract excerpt

Patient stratification has been instrumental for the success of targeted therapies in breast cancer. However, the molecular basis of metastatic breast cancer and its therapeutic vulnerabilities remain poorly understood. Here we show that PML is a novel target in aggressive breast cancer. The acquisition of aggressiveness and metastatic features in breast tumours is accompanied by the elevated PML expression and...

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PMID: 27553708
DOI: 10.1038/ncomms12595

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