Article
Concomitant Use of Proton Pump Inhibitors and Clopidogrel Is Not Associated with Adverse Outcomes after Ischemic Stroke in Chinese Population.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Dec 2016
Yi Xingyang, Zhou Qiang, Wang Chun, Lin Jing, Cheng Wen, Chi Lifen
Abstract excerpt
BACKGROUND AND PURPOSE: Conflicting data exist as to whether proton pump inhibitors (PPIs) diminish the efficacy of clopidogrel. We, therefore, assessed the effect of concomitant PPI use in ischemic stroke (IS) patients receiving clopidogrel. METHODS: We consecutively enrolled 535 IS patients receiving clopidogrel, 166 of whom were concomitantly taking PPIs. Platelet aggregation was measured before and after 7-10...
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