Analysis of Cyclin-Dependent Kinase Inhibitor-2B rs1063192 Polymorphism in Saudi Patients with Primary Open-Angle Glaucoma.

doi:10.1089/gtmb.2016.0140

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Article

Analysis of Cyclin-Dependent Kinase Inhibitor-2B rs1063192 Polymorphism in Saudi Patients with Primary Open-Angle Glaucoma.

Genetic testing and molecular biomarkers - 1 Oct 2016

Abu-Amero Khaled K, Kondkar Altaf A, Mousa Ahmed, Almobarak Faisal A, Alawad Abdullah, Altuwaijri Saleh, Sultan Tahira, Azad Taif A, Al-Obeidan Saleh A

Abstract excerpt

AIMS: To investigate whether the polymorphism rs1063192 (A>G) in the cyclin-dependent kinase Inhibitor-2B (CDKN2B) gene is a risk factor for primary open-angle glaucoma (POAG). METHOD: A case-control study was conducted wherein we genotyped 87 unrelated POAG cases and 94 control subjects from Saudi Arabia using the Taq-Man® assay. RESULTS: The minor allele frequency was 0.20 in POAG cases and 0.21 in controls....

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PMID: 27541204
DOI: 10.1089/gtmb.2016.0140

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