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Article

Effects of steam autoclave treatment on Geobacillus stearothermophilus spores.

Journal of applied microbiology - 1 Nov 2016

Huesca-Espitia L C, Suvira M, Rosenbeck K, Korza G, Setlow B, Li W, Wang S, Li Y-Q, Setlow P

Abstract excerpt

AIMS: To determine the mechanism of autoclave killing of Geobacillus stearothermophilus spores used in biological indicators (BIs) for steam autoclave sterilization, and rates of loss of spore viability and a spore enzyme used in BIs. METHODS AND RESULTS: Spore viability, dipicolinic acid (DPA) release, nucleic acid staining, α-glucosidase activity, protein structure and mutagenesis were measured during...

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PMID: 27538778
DOI: 10.1111/jam.13257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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