Article
Prediction of Protection against Asian Enterovirus 71 Outbreak Strains by Cross-neutralizing Capacity of Serum from Dutch Donors, The Netherlands.
Emerging infectious diseases - 1 Sept 2016
van der Sanden Sabine M G, Koen Gerrit, van Eijk Hetty, Koekkoek Sylvie M, de Jong Menno D, Wolthers Katja C
Abstract excerpt
Outbreaks of human enterovirus 71 (EV-71) in Asia are related to high illness and death rates among children. To gain insight into the potential threat for the population of Europe, we determined the neutralizing activity in intravenous immunoglobulin (IVIg) batches and individual serum samples from donors in the Netherlands against EV-71 strains isolated in Europe and in Asia. All IVIg batches and 41%, 79%, and...
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