Article
Neutralization of five subgenotypes of Enterovirus 71 by Taiwanese human plasma and Taiwanese plasma derived intravenous immunoglobulin.
Biologicals : journal of the International Association of Biological Standardization - 1 May 2013
Wu Chi-Yu, Wang Hsiu-Chi, Wang Kun-Teng, Weng Shu-Ching, Chang Wei-Hao, Shih Daniel Yang-Chih, Lo Chi-Fang, Wang Der-Yuan
Abstract excerpt
Enterovirus 71 (EV71) commonly occurs in children, causing hand, foot and mouth disease (HFMD) in about 29% of patients. Studies have suggested that patients develop meningitis and encephalopathy with a mortality rate of 4-26%. EV71 subgenotypes including B4, B5, C2, C4 and C5 have caused HFMD epidemics in Taiwan. In terms of therapeutical strategy, intravenous immunoglobulin (IVIG) has been shown to improve...
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