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Article

Investigation of a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population: A Family-Based Study.

PloS one - 1 Jan 2016

Dong He, Liu Wenmiao, Liu Meixin, Xu Longqiang, Li Qiang, Zhang Ru, Zhang Xin, Liu Shiguo

Abstract excerpt

Tourette syndrome (TS) is a polygenic neuropsychiatric disease. Previous studies have indicated that dysregulation in the histaminergic system may play a crucial role in disease onset. In this study, we investigated the role of the histidine decarboxylase gene (HDC) in TS susceptibility in the Chinese Han population. After genotyping 241 TS nuclear families trios, we analyzed three tag HDC single nucleotide...

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Identifiers

PMID: 27529419
DOI: 10.1371/journal.pone.0160265
PMCID: PMC4986944

Genes

HDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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