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Article

Recurrent <i>TRIO</i> Fusion in Nontranslocation–Related Sarcomas

15 Aug 2016

Abstract excerpt

PURPOSE: Despite various differences, nontranslocation-related sarcomas (e.g., comprising undifferentiated pleomorphic sarcoma, leiomyosarcoma, myxofibrosarcoma) are unified by their complex genetics. Extensive analysis of the tumor genome using molecular cytogenetic approaches showed many chromosomal gains, losses, and translocations per cell. Genomic quantitative alterations and expression variations have been...

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PMID: 27528700
DOI: 10.1158/1078-0432.ccr-16-0290

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