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Article

Targeted Exome Sequencing of the Cancer Genome in Patients with Very High-risk Bladder Cancer.

European urology - 1 Nov 2016

Longo Thomas, McGinley Kathleen F, Freedman Jennifer A, Etienne Wiguins, Wu Yuan, Sibley Alexander, Owzar Kouros, Gresham Jeremy, Moy Christopher, Szabo Stephen, Greshock Joel, Zhou Hui, Bai Yuchen, Inman Brant A

Abstract excerpt

We completed targeted exome sequencing of the tumors of 50 patients with pTis-pT4b bladder cancer. Mutations were categorized by type, stratified against previously identified cancer loci in the Catalogue of Somatic Mutations in Cancer and The Cancer Genome Atlas databases, and evaluated in pathway analysis and comutation plots. We analyzed mutation associations with receipt of neoadjuvant chemotherapy, nodal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27520487
DOI: 10.1016/j.eururo.2016.07.049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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