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Article

Involvement of NK Cells and NKp30 Pathway in Antisynthetase Syndrome.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2016

Hervier Baptiste, Perez Mikaël, Allenbach Yves, Devilliers Hervé, Cohen Fleur, Uzunhan Yurdagül, Ouakrim Hanane, Dorgham Karim, Méritet Jean-François, Longchampt Elisabeth, Stenzel Werner, Cremer Isabelle, Benveniste Olivier, Vieillard Vincent

Abstract excerpt

Antisynthetase syndrome (aSS) is characterized by the association of interstitial lung disease and myositis with anti-tRNA synthetase autoantibodies. Immune mechanisms leading to aSS could be initiated in the lungs, but the role of NK cells has not yet been studied. Both extensive NK cell phenotype and functions were compared between 33 patients and 26 controls. Direct and redirected polyfunctionality assays...

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Identifiers

PMID: 27511738
DOI: 10.4049/jimmunol.1501902

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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