Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of DNA methylation in ST6Gal1 expression in gliomas.

Glycobiology - 1 Dec 2016

Kroes Roger A, Moskal Joseph R

Abstract excerpt

The mechanism of transcriptional silencing of ST6Gal1 in gliomas has not yet been elucidated. Multiple independent promoters govern the expression of the ST6Gal I gene. Here, we investigated whether epigenetic abnormalities involving DNA methylation affect ST6Gal1 expression. Transcript-specific qRT-PCR following exposure of glioma cell lines to 5-aza-2'-deoxycytidine (5-aza-dC), a DNA methyltransferase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cell Line, Tumor
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Phenotype

Share to Promoter Regions, Genetic

Share to Sialyltransferases

Source

Identifiers

PMID: 27510958
DOI: 10.1093/glycob/cww058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The role of DNA methylation in ST6Gal1 expression in gliomas.PMID 27510958Read ↗

CRISPR activation screens map the genomic landscape of cancer glycome remodelingSemantic proximity Read ↗

Profiling the Regulatory Landscape of Sialylation through miRNA Targeting of CMP- Sialic Acid SynthetaseSemantic proximity Read ↗

Characterization of P1 promoter activity of the beta-galactoside alpha2,6-sialyltransferase I gene (siat 1) in cervical and hepatic cancer cell lines.Semantic proximity Read ↗

Sialylation is involved in cell fate decision during development, reprogramming and cancer progressionSemantic proximity Read ↗

α2-6–Linked Sialic Acids on N-Glycans Modulate Carcinoma Differentiation <i>In vivo</i>Semantic proximity Read ↗

Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia.Semantic proximity Read ↗

β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.Semantic proximity Read ↗

Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.