Article

DeepADR: Multi-modal Prediction of Adverse Drug Reaction Frequency by Integrating Early-Stage Drug Discovery Information via Kolmogorov-Arnold Networks

2025-08-01

Abstract excerpt

Adverse drug reactions (ADRs) are a major cause of clinical trial failure and post-market withdrawal, posing significant risks to public health and impeding drug development. While computational methods offer an alternative to costly preclinical testing, existing models often fail with novel compounds by requiring pre-existing information such as drug-ADR associations or by inadequately integrating diverse data so...

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Literature Corpus work: 59a68fdf-7f5f-5e11-8d31-faea88199a87
DOI: 10.1101/2025.07.29.667409

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