A human neurodevelopmental model for Williams syndrome.

doi:10.1038/nature19067

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Article

A human neurodevelopmental model for Williams syndrome.

Nature - 18 Aug 2016

Chailangkarn Thanathom, Trujillo Cleber A, Freitas Beatriz C, Hrvoj-Mihic Branka, Herai Roberto H, Yu Diana X, Brown Timothy T, Marchetto Maria C, Bardy Cedric, McHenry Lauren, Stefanacci Lisa, Järvinen Anna, Searcy Yvonne M, DeWitt Michelle, Wong Wenny, Lai Philip, Ard M Colin, Hanson Kari L, Romero Sarah, Jacobs Bob, Dale Anders M, Dai Li, Korenberg Julie R, Gage Fred H, Bellugi Ursula, Halgren Eric, Semendeferi Katerina, Muotri Alysson R

Abstract excerpt

Williams syndrome is a genetic neurodevelopmental disorder characterized by an uncommon hypersociability and a mosaic of retained and compromised linguistic and cognitive abilities. Nearly all clinically diagnosed individuals with Williams syndrome lack precisely the same set of genes, with breakpoints in chromosome band 7q11.23 (refs 1-5). The contribution of specific genes to the neuroanatomical and functional...

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PMID: 27509850
DOI: 10.1038/nature19067
PMCID: PMC4995142

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FZD9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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