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Article

From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?

Clinical nephrology - 1 Jan 2000

Olabisi Opeyemi, Al-Romaih Khaldoun, Henderson Joel, Tomar Ritu, Drummond Iain, MacRae Calum, Pollak Martin

Abstract excerpt

BACKGROUND: Risk variant Apolipoprotein L1 (G1/G2) are strongly associated with a spectrum of kidney disease in people of recent African descent. The mechanism of ApoL1 nephropathy is unknown. Podocytes and/or endothelial cells are the presumed target kidney cells. Given the close homology in structure and function of zebrafish (ZF) pronephros and human nephron, we studied the effect of podocyte-specific or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27509583
DOI: 10.5414/CNP86S116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?PMID 27509583Read ↗

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