Article
Inducing and Quantifying Clostridium difficile Spore Formation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Shen Aimee, Fimlaid Kelly A, Pishdadian Keyan
Abstract excerpt
The Gram-positive nosocomial pathogen Clostridium difficile induces sporulation during growth in the gastrointestinal tract. Sporulation is necessary for this obligate anaerobe to form metabolically dormant spores that can resist antibiotic treatment, survive exit from the mammalian host, and transmit C. difficile infections. In this chapter, we describe a method for inducing C. difficile sporulation in vitro....
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