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Article

ORM Expression Alters Sphingolipid Homeostasis and Differentially Affects Ceramide Synthase Activity.

Plant physiology - 1 Oct 2016

Kimberlin Athen N, Han Gongshe, Luttgeharm Kyle D, Chen Ming, Cahoon Rebecca E, Stone Julie M, Markham Jennifer E, Dunn Teresa M, Cahoon Edgar B

Abstract excerpt

Sphingolipid synthesis is tightly regulated in eukaryotes. This regulation in plants ensures sufficient sphingolipids to support growth while limiting the accumulation of sphingolipid metabolites that induce programmed cell death. Serine palmitoyltransferase (SPT) catalyzes the first step in sphingolipid biosynthesis and is considered the primary sphingolipid homeostatic regulatory point. In this report,...

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Identifiers

PMID: 27506241
DOI: 10.1104/pp.16.00965
PMCID: PMC5047106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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