Article
Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity.
The Plant cell - 1 Nov 2013
Kimberlin Athen N, Majumder Saurav, Han Gongshe, Chen Ming, Cahoon Rebecca E, Stone Julie M, Dunn Teresa M, Cahoon Edgar B
Abstract excerpt
Maintenance of sphingolipid homeostasis is critical for cell growth and programmed cell death (PCD). Serine palmitoyltransferase (SPT), composed of LCB1 and LCB2 subunits, catalyzes the primary regulatory point for sphingolipid synthesis. Small subunits of SPT (ssSPT) that strongly stimulate SPT activity have been identified in mammals, but the role of ssSPT in eukaryotic cells is unclear. Candidate Arabidopsis...
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