Article
Balancing roles between phosphatidylinositols and sphingolipids in regulating immunity and ER stress responses in pi4kβ1,2.
The Plant journal : for cell and molecular biology - 1 Sept 2024
Thulasi Devendrakumar Karen, Herrfurth Cornelia, Yeap Mikaela, Peng Tony ShengZhe, Feussner Ivo, Li Xin
Abstract excerpt
Plant immune regulation is complex. In addition to proteins, lipid molecules play critical roles in modulating immune responses. The mutant pi4kβ1,2 is mutated in two phosphatidylinositol 4-kinases PI4Kβ1 and β2 involved in the biosynthesis of phosphatidylinositol 4-phosphate (PI4P). The mutant displays autoimmunity, short roots, aberrant root hairs, and a heightened sensitivity to ER stress. In a forward genetic...
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