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Article

Re-emergence of H3N2 strains carrying potential neutralizing mutations at the N-linked glycosylation site at the hemagglutinin head, post the 2009 H1N1 pandemic.

BMC infectious diseases - 8 Aug 2016

Ushirogawa Hiroshi, Naito Tadasuke, Tokunaga Hirotoshi, Tanaka Toshihiro, Nakano Takashi, Terada Kihei, Ohuchi Masanobu, Saito Mineki

Abstract excerpt

BACKGROUND: Seasonally prevalent H1N1 and H3N2 influenza A viruses have evolved by antigenic drift; this evolution has resulted in the acquisition of asparagine (N)-linked glycosylation sites (NGSs) in the globular head of hemagglutinin (HA), thereby affecting the antigenic and receptor-binding properties, as well as virulence. An epidemiological survey indicated that although the traditional seasonal H1N1 strain...

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Identifiers

PMID: 27503338
DOI: 10.1186/s12879-016-1738-1
PMCID: PMC4977674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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