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Article

Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2013

Job Emma R, Deng Yi-Mo, Barfod Kenneth K, Tate Michelle D, Caldwell Natalie, Reddiex Scott, Maurer-Stroh Sebastian, Brooks Andrew G, Reading Patrick C

Abstract excerpt

Seasonal influenza A viruses (IAV) originate from pandemic IAV and have undergone changes in antigenic structure, including addition of glycans to the viral hemagglutinin (HA). Glycans on the head of HA promote virus survival by shielding antigenic sites, but highly glycosylated seasonal IAV are inactivated by soluble lectins of the innate immune system. In 2009, human strains of pandemic H1N1 [A(H1N1)pdm]...

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Identifiers

PMID: 23365085
DOI: 10.4049/jimmunol.1202433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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