Article
Characterization and functional studies of fowl adenovirus 9 dUTPase.
Virology - 1 Oct 2016
Deng Li, Qin Xiaobing, Krell Peter, Lu Ray, Sharif Shayan, Nagy Éva
Abstract excerpt
Deoxyuridine 5'-triphosphate pyrophosphatase (dUTPase), a ubiquitous enzyme that catalyzes the hydrolysis of dUTP to dUMP and found in many viruses, has yet to be identified in fowl adenovirus 9 (FAdV-9). By a multiple alignment of dUTPase amino acid sequences, FAdV-9 ORF1 contained the five conserved motifs that define the protein family, and encoded a functional dUTPase. Moreover, transcription and protein...
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