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Article

Defining a new aggressiveness classification and using NFATc1 localization as a prognostic factor in cherubism.

Human pathology - 1 Dec 2016

Kadlub Natacha, Sessiecq Quentin, Dainese Linda, Joly Aline, Lehalle Daphne, Marlin Sandrine, Badoual Cecile, Galmiche Louise, Majoufre-Lefebvre Claire, Berdal Ariane, Deckert Marcel, Vazquez Marie-Paule, Descroix Vianney, Coudert Amélie E, Picard Arnaud

Abstract excerpt

Cherubism is a rare genetic disease characterized by bilateral giant cell reparative granuloma of the jaws consisting of a fibrotic stroma with giant multinucleated cells (GMCs) and osteoclastic features. Cherubism severity is highly variable, and recurrence after surgery is the most important risk. Currently, there are no prognostic indicators. The aims of this study were to evaluate the osteoclastogenesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27498064
DOI: 10.1016/j.humpath.2016.07.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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