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Article

SH3BP2 is rarely mutated in exon 9 in giant cell lesions outside cherubism.

Clinical orthopaedics and related research - 1 Jun 2007

Lietman Steven A, Prescott Nichole L, Hicks David G, Westra William H, Levine Michael A

Abstract excerpt

Giant cell tumor of bone and giant cell reparative granuloma are benign lesions with prominent giant (multinucleated) cells, and an understanding of the molecular biology and genetics of these lesions will likely aid in more effective treatment. Cherubism is a benign lesion of the maxilla and man...

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PMID: 17545756
DOI: 10.1097/BLO.0b013e31804b4131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17545756-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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SH3BP2 is rarely mutated in exon 9 in giant cell lesions outside cherubism.PMID 17545756Read ↗

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NFATc1 and TNFalpha expression in giant cell lesions of the jaws.Semantic proximity Read ↗

Analysis of giant cell tumour of bone cells for Noonan syndrome/cherubism-related mutations.Semantic proximity Read ↗

Multiple versus solitary giant cell lesions of the jaw: Similar or distinct entities?Semantic proximity Read ↗

Giant cell tumor of soft tissue is genetically distinct from its bone counterpart.Semantic proximity Read ↗

DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell‐rich histological mimicsSemantic proximity Read ↗

SH3BP2-encoding exons involved in cherubism are not associated with central giant cell granuloma.Semantic proximity Read ↗

Defining a new aggressiveness classification and using NFATc1 localization as a prognostic factor in cherubism.Semantic proximity Read ↗

Exploring a cherubism bone phenotype outside the craniofacial region.Semantic proximity Read ↗

SH3BP2-related fibro-osseous disorders of the maxilla and mandible: A systematic review.Semantic proximity Read ↗

[Gene mutation and expression of SH-3BP-2 in cherubism].Semantic proximity Read ↗

Giant cell tumor of bone: updated molecular pathogenesis and tumor biology.Semantic proximity Read ↗

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