Article
Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.
Head and neck pathology - 1 Mar 2018
Argyris Prokopios P, Gopalakrishnan Rajaram, Hu Ying, Reichenberger Ernst J, Koutlas Ioannis G
Abstract excerpt
Cherubism is a rare autosomal dominant condition affecting the jaws and caused by mutations in the gene encoding for the adapter protein SH3BP2 that maps to chromosome 4p16.3. Cherubism is characterized by symmetrically developing bone lesions in the maxilla and mandible. The lesions have been radiographically and histopathologically well-described. Here, we present a family with cherubism with two of its members...
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