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Article

scphaser: haplotype inference using single-cell RNA-seq data.

Bioinformatics (Oxford, England) - 1 Oct 2016

Edsgärd Daniel, Reinius Björn, Sandberg Rickard

Abstract excerpt

UNLABELLED: Determination of haplotypes is important for modelling the phenotypic consequences of genetic variation in diploid organisms, including cis-regulatory control and compound heterozygosity. We realized that single-cell RNA-seq (scRNA-seq) data are well suited for phasing genetic variants, since both transcriptional bursts and technical bottlenecks cause pronounced allelic fluctuations in individual...

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Identifiers

PMID: 27497440
DOI: 10.1093/bioinformatics/btw484
PMCID: PMC5039928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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