Article
Clinical use of ruxolitinib in an academic medical center in unselected patients with myeloproliferative neoplasms not on clinical study.
Leukemia & lymphoma - 1 Apr 2017
Naqvi Kiran, Daver Naval, Pemmaraju Naveen, Bose Prithviraj, Garcia-Manero Guillermo, Cortes Jorge, Kantarjian Hagop M, Verstovsek Srdan
Abstract excerpt
Ruxolitinib is the only approved therapy for myelofibrosis (MF). However, its use in patients with myeloproliferative neoplasms (MPN) not participating in clinical studies has been poorly described. We reviewed the medical records of 45 patients (35 MF, 10 others) treated with ruxolitinib at our center, off clinical study, during the year after its approval. Patients had advanced features and were refractory to...
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