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Article

Who Is in the Driver's Seat: Tracing Cancer Genes Using CRISPR-Barcoding.

Molecular cell - 4 Aug 2016

Drost Jarno, Clevers Hans

Abstract excerpt

Intratumor heterogeneity is thought to be the driving force of tumor evolution and therapy resistance. Yet tools to study these processes are limited. In this issue, Guernet et al. (2016) devised clustered regularly interspaced short palindromic repeats (CRISPR)-barcoding to functionally annotate specific mutations and study clonal evolution in heterogeneous cell populations.

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Identifiers

PMID: 27494556
DOI: 10.1016/j.molcel.2016.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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