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Article

HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo.

Oncotarget - 30 Aug 2016

Xi Ruxing, Pan Shupei, Chen Xin, Hui Beina, Zhang Li, Fu Shenbo, Li Xiaolong, Zhang Xuanwei, Gong Tuotuo, Guo Jia, Zhang Xiaozhi, Che Shaomin

Abstract excerpt

High-risk human papillomavirus (HPV), especially HPV16, correlates with cancerogenesis of human esophageal squamous cell carcinoma (ESCC) and we have reported that HPV16 related with a poor prognosis of ESCC patients in China. We aim to investigate the potential role and mechanism of HPV16 in ESCC development and progress. Our following researches demonstrated that ESCC cells which were stably transfected by...

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Identifiers

PMID: 27489353
DOI: 10.18632/oncotarget.10959
PMCID: PMC5302972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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