Article
Regulation of Ebola virus VP40 matrix protein by SUMO.
Scientific reports - 16 Nov 2016
Baz-Martínez Maite, El Motiam Ahmed, Ruibal Paula, Condezo Gabriela N, de la Cruz-Herrera Carlos F, Lang Valerie, Collado Manuel, San Martín Carmen, Rodríguez Manuel S, Muñoz-Fontela Cesar, Rivas Carmen
Abstract excerpt
The matrix protein of Ebola virus (EBOV) VP40 regulates viral budding, nucleocapsid recruitment, virus structure and stability, viral genome replication and transcription, and has an intrinsic ability to form virus-like particles. The elucidation of the regulation of VP40 functions is essential to identify mechanisms to inhibit viral replication and spread. Post-translational modifications of proteins with...
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