Article
Effects of ankyrin 3 gene risk variants on brain structures in patients with bipolar disorder and healthy subjects.
Psychiatry and clinical neurosciences - 1 Nov 2016
Ota Miho, Hori Hiroaki, Sato Noriko, Yoshida Fuyuko, Hattori Kotaro, Teraishi Toshiya, Kunugi Hiroshi
Abstract excerpt
AIM: The intronic single-nucleotide polymorphism rs10994336 of the ankyrin 3 gene (ANK3 ) is one of the genome-wide supported risk variants for bipolar disorder (BD), and the T-allele of rs10761482 is also reported to have relevance to BD. We investigated the effect of ANK3 rs10761482 genetic variation on brain structure. METHODS: Subjects were 43 BD patients and 229 healthy volunteers. We evaluated the effects...
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