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Article

Cognitive effects of the ANK3 risk variants in patients with bipolar disorder and healthy individuals.

Journal of affective disorders - 1 Apr 2014

Hori Hiroaki, Yamamoto Noriko, Teraishi Toshiya, Ota Miho, Fujii Takashi, Sasayama Daimei, Matsuo Junko, Kinoshita Yukiko, Hattori Kotaro, Nagashima Anna, Ishida Ikki, Koga Norie, Higuchi Teruhiko, Kunugi Hiroshi

Abstract excerpt

BACKGROUND: Genetic variants within the ankyrin 3 gene (ANK3) have been identified as a risk factor for bipolar disorder. ANK3 influences action potential generation by clustering sodium gated channels and plays an integral role in neurotransmission. Thus, this gene may influence cognition, a process compromised in bipolar disorder. We investigated whether genetic variants of ANK3 would be associated with an...

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Source

Identifiers

PMID: 24655771
DOI: 10.1016/j.jad.2014.02.008

Genes

ANK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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