Article
Frontotemporal dementia and language networks: cortical thickness reduction is driven by dyslexia susceptibility genes.
Scientific reports - 3 Aug 2016
Paternicó Donata, Manes Marta, Premi Enrico, Cosseddu Maura, Gazzina Stefano, Alberici Antonella, Archetti Silvana, Bonomi Elisa, Cotelli Maria Sofia, Cotelli Maria, Turla Marinella, Micheli Anna, Gasparotti Roberto, Padovani Alessandro, Borroni Barbara
Abstract excerpt
Variations within genes associated with dyslexia result in a language network vulnerability, and in patients with Frontotemporal Dementia (FTD), language disturbances represent a disease core feature. Here we explored whether variations within three related-dyslexia genes, namely KIAA0319, DCDC2, and CNTNAP, might affect cortical thickness measures in FTD patients. 112 FTD patients underwent clinical and...
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