Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.

doi:10.1007/s11682-015-9392-6

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Article

Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.

Brain imaging and behavior - 1 Mar 2016

Eicher John D, Montgomery Angela M, Akshoomoff Natacha, Amaral David G, Bloss Cinnamon S, Libiger Ondrej, Schork Nicholas J, Darst Burcu F, Casey B J, Chang Linda, Ernst Thomas, Frazier Jean, Kaufmann Walter E, Keating Brian, Kenet Tal, Kennedy David, Mostofsky Stewart, Murray Sarah S, Sowell Elizabeth R, Bartsch Hauke, Kuperman Joshua M, Brown Timothy T, Hagler Donald J, Dale Anders M, Jernigan Terry L, Gruen Jeffrey R

Abstract excerpt

Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0319, ACOT13, and FAM65B with reading-, language-, and IQ-related traits. Additionally, the effects of reading-associated DYX3 markers were recently characterized using structural neuroimaging techniques....

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Identifiers

PMID: 25953057
DOI: 10.1007/s11682-015-9392-6
PMCID: PMC4639472

Genes

KIAA0319
ACOT13
DCDC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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