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Article

Zinc-desferrioxamine attenuates retinal degeneration in the rd10 mouse model of retinitis pigmentosa.

Free radical biology & medicine - 15 Oct 2011

Obolensky Alexey, Berenshtein Eduard, Lederman Michal, Bulvik Baruch, Alper-Pinus Ruslana, Yaul Ruth, Deleon Efrat, Chowers Itay, Chevion Mordechai, Banin Eyal

Abstract excerpt

Iron-associated oxidative injury plays a role in retinal degeneration such as age-related macular degeneration and retinitis pigmentosa. The metallo-complex zinc-desferrioxamine (Zn/DFO) may ameliorate such injury by chelation of labile iron in combination with release of zinc. We explored whether Zn/DFO can affect the course of retinal degeneration in the rd10 mouse model of retinitis pigmentosa. Zn/DFO-treated...

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PMID: 21824515
DOI: 10.1016/j.freeradbiomed.2011.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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