Article
Acanthamoeba castellanii Genotype T4 Stimulates the Production of Interleukin-10 as Well as Proinflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells, and Human Monocyte-Derived Macrophages.
Infection and immunity - 1 Oct 2016
Mattana Antonella, Sanna Manuela, Cano Antonella, Delogu Giuseppe, Erre Giuseppe, Roberts Craig W, Henriquez Fiona L, Fiori Pier Luigi, Cappuccinelli Piero
Abstract excerpt
Free-living amoebae of the genus Acanthamoeba can cause severe and chronic infections in humans, mainly localized in immune privileged sites, such as the brain and the eye. Monocytes/macrophages are thought to be involved in Acanthamoeba infections, but little is known about how these facultative parasites influence their functions. The aim of this work was to investigate the effects of Acanthamoeba on human...
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