Article
CTLA-4 and IL-6 gene polymorphisms: Risk factors for recurrent pregnancy loss.
Human immunology - 1 Dec 2016
Nasiri Mahboobeh, Rasti Zarnegar
Abstract excerpt
The purpose of the present study was to evaluate the possible association between CTLA-4 +49A/G and IL-6 -634C/G polymorphisms, and the risk of recurrent pregnancy loss (RPL). 240 women (120 healthy controls and 120 with RPL) were enrolled in this case-control study. Genotyping was performed using a PCR-RFLP technique. In the case of polymorphic CTLA-4 +49A/G, the wild type allele G was associated with a...
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