Article
Effects of interleukin-1 receptor antagonist (IL-1Ra) gene 86 bp VNTR polymorphism on recurrent pregnancy loss: a case-control study.
Hormone molecular biology and clinical investigation - 26 May 2017
Hajizadeh Yasamin Sayed, Emami Elina, Nottagh Marina, Amini Zahra, Maroufi Nazila Fathi, Azimian Saba Haj, Isazadeh Alireza
Abstract excerpt
Objective Recurrent pregnancy loss (RPL) is a heterogeneous disease which is defined as two or more consecutive fetal losses during early pregnancy. Interleukin-1 receptor antagonist (IL-1Ra) is a anti-inflammatory cytokine, which inhibits IL-1 activity by binding to its receptors. The aim of this study was to investigate the association between RPL and IL-1Ra intron 2 polymorphism (86 bp VNTR) in Iranian women....
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