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Article

Sequencing Structural Variants in Cancer for Precision Therapeutics.

Trends in genetics : TIG - 1 Sept 2016

Macintyre Geoff, Ylstra Bauke, Brenton James D

Abstract excerpt

The identification of mutations that guide therapy selection for patients with cancer is now routine in many clinical centres. The majority of assays used for solid tumour profiling use DNA sequencing to interrogate somatic point mutations because they are relatively easy to identify and interpret. Many cancers, however, including high-grade serous ovarian, oesophageal, and small-cell lung cancer, are driven by...

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Identifiers

PMID: 27478068
DOI: 10.1016/j.tig.2016.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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