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Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain

12 Jul 2016

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is a devastating brain disorder with no effective treatment or cure available. The scarcity of brain tissue makes it hard to study changes in the brain and impossible to perform longitudinal studies. However, peripheral pathology in HD suggests that it is possible to study the disease using peripheral tissue as a monitoring tool for disease progression and/or efficacy of...

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PMID: 27476530
DOI: 10.1186/s13023-016-0475-2

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