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Article

Altered gut microbiota in Rett syndrome

30 Jul 2016

Abstract excerpt

BACKGROUND: The human gut microbiota directly affects human health, and its alteration can lead to gastrointestinal abnormalities and inflammation. Rett syndrome (RTT), a progressive neurological disorder mainly caused by mutations in MeCP2 gene, is commonly associated with gastrointestinal dysfunctions and constipation, suggesting a link between RTT's gastrointestinal abnormalities and the gut microbiota. The...

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PMID: 27473171
DOI: 10.1186/s40168-016-0185-y

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