Article
Microbial community changes in a female rat model of Rett syndrome.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Jul 2021
Gallucci A, Patterson K C, Weit A R, Van Der Pol W J, Dubois L G, Percy A K, Morrow C D, Campbell S L, Olsen M L
Abstract excerpt
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder that is predominantly caused by alterations of the methyl-CpG-binding protein 2 (MECP2) gene. Disease severity and the presence of comorbidities such as gastrointestinal distress vary widely across affected individuals. The gut microbiome has been implicated in neurodevelopmental disorders such as Autism Spectrum Disorder (ASD) as a regulator of...
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