Article
Differential tumor infiltration by T-cells characterizes intrinsic molecular subtypes in breast cancer.
Journal of translational medicine - 29 Jul 2016
Miyan M, Schmidt-Mende J, Kiessling R, Poschke I, de Boniface J
Abstract excerpt
BACKGROUND: Molecular subtypes of breast cancer and presence of tumor-infiltrating immune cells have both been implicated as important predictive and prognostic factors for improved risk stratification and treatment individualization of breast cancer patients. Their association, however, has not been studied in detail. The aim of this study was to evaluate the expression of the T cell markers CD8, FoxP3, CD3 and...
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