Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of inflammatory infiltrates in triple negative breast cancer.

Journal of clinical pathology - 1 Jul 2015

Matsumoto Hirofumi, Koo Si-lin, Dent Rebecca, Tan Puay Hoon, Iqbal Jabed

Abstract excerpt

Triple negative breast cancer (TNBC) is a heterogenous disease often characterised by aggressive biology and poor prognosis. Efforts to precisely treat TNBC have been compounded by the lack of specific therapeutic molecular targets. Recent transcriptomic studies have revealed, among others, an immunomodulatory subtype of TNBC, whereby activated immune response genes are associated with good prognosis. Since then,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to CD8-Positive T-Lymphocytes
Share to Immunotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Lymphocytes, Tumor-Infiltrating

Share to Macrophages

Share to Triple Negative Breast Neoplasms

Share to Tumor Microenvironment

Source

Identifiers

PMID: 25750267
DOI: 10.1136/jclinpath-2015-202944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of inflammatory infiltrates in triple negative breast cancer.PMID 25750267Read ↗

A Comprehensive Immunologic Portrait of Triple-Negative Breast CancerSemantic proximity Read ↗

Immune Milieu and Genomic Alterations Set the Triple-Negative Breast Cancer Immunomodulatory Subtype Tumor BehaviorSemantic proximity Read ↗

Classification of triple-negative breast cancer based on immune cell infiltrationSemantic proximity Read ↗

Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancerSemantic proximity Read ↗

Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast CancerSemantic proximity Read ↗

Immunogenomic Landscape in Breast Cancer Reveals Immunotherapeutically Relevant Gene Signatures.Semantic proximity Read ↗

Immune Landscape of Breast CancersSemantic proximity Read ↗

Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness.Semantic proximity Read ↗

CRTAM promotes antitumor immune response in triple negative breast cancer by enhancing CD8+ T cell infiltrationSemantic proximity Read ↗

Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancerSemantic proximity Read ↗

Comprehensive genomic and immunophenotypic analysis of CD4 T cell infiltrating human triple-negative breast cancerSemantic proximity Read ↗

Clinical relevance of the immune contexture and AXL kinase in triple-negative breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.