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Article

Impact of increased mutagenesis on adaptation to high temperature in bacteriophage Qβ.

Virology - 1 Oct 2016

Arribas María, Cabanillas Laura, Kubota Kirina, Lázaro Ester

Abstract excerpt

RNA viruses replicate with very high error rates, which makes them more sensitive to additional increases in this parameter. This fact has inspired an antiviral strategy named lethal mutagenesis, which is based on the artificial increase of the error rate above a threshold incompatible with virus infectivity. A relevant issue concerning lethal mutagenesis is whether incomplete treatments might enhance the...

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Identifiers

PMID: 27471955
DOI: 10.1016/j.virol.2016.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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