Article
Identification of mutations conferring 5-azacytidine resistance in bacteriophage Qβ.
Virology - 1 Sept 2011
Arribas María, Cabanillas Laura, Lázaro Ester
Abstract excerpt
RNA virus replication takes place at a very high error rate, and additional increases in this parameter can produce the extinction of virus infectivity. Nevertheless, RNA viruses can adapt to conditions of increased mutagenesis, which demonstrates that selection of beneficial mutations is also possible at higher-than-standard error rates. In this study we have analysed the evolutionary behaviour of bacteriophage...
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