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Article

cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness.

Scientific reports - 29 Jul 2016

Wiley Luke A, Burnight Erin R, DeLuca Adam P, Anfinson Kristin R, Cranston Cathryn M, Kaalberg Emily E, Penticoff Jessica A, Affatigato Louisa M, Mullins Robert F, Stone Edwin M, Tucker Budd A

Abstract excerpt

Immunologically-matched, induced pluripotent stem cell (iPSC)-derived photoreceptor precursor cells have the potential to restore vision to patients with retinal degenerative diseases like retinitis pigmentosa. The purpose of this study was to develop clinically-compatible methods for manufacturing photoreceptor precursor cells from adult skin in a non-profit cGMP environment. Biopsies were obtained from 35 adult...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27471043
DOI: 10.1038/srep30742
PMCID: PMC4965859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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