Article
Disease-specific T-helper cell polarizing function of lesional dendritic cells in different types of chronic rhinosinusitis with nasal polyps.
American journal of respiratory and critical care medicine - 15 Sept 2014
Shi Li-Li, Song Jia, Xiong Peng, Cao Ping-Ping, Liao Bo, Ma Jin, Zhang Ya-Na, Zeng Ming, Liu Yang, Wang Heng, Cui Yong-Hua, Huang Shau-Ku, Liu Zheng
Abstract excerpt
RATIONALE: Although eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit distinct T-helper (Th) responses, the underlying mechanisms remain unclear. OBJECTIVES: To clarify the phenotypes and Th-cell polarizing functions of dendritic cells (DCs) in different types of CRSwNP. METHODS: DC subsets, their surface phenotypes, and Th-cell subsets were studied by means of...
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